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The buffy coat is the fraction of uncoagulated blood that contains most of the white blood cells and platelets after a density gradient centrifugation process. Once the centrifugation is carried out, three differentiated layers can be distinguished, one of transparent liquid (plasma), another layer of red liquid that contains most of the red blood cells, and a thin layer in the middle (buffy coat) that contains the most white blood cells and platelets.
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Buffy Coats Features
Source: The whole blood is collected at one of our 10 licensed blood centers located in the US (Memphis, Miami, Philadelphia, Baltimore, Jackson, Temple and Louisville) or at one of our more than 30 blood collection centers in Germany. Whole blood is further processed in our processing centers to produce the buffy coats.
Donors Criteria: Donors have an approved consent for donating blood. All donors are screened to ensure that each of them is in good health condition and that products are not collected from a high-risk population for blood-borne infections.
Donor Data Provided: Age, gender, race and blood group.
Use: Research and Development. Bulk quantities also available for further manufacturing of IVD reagents.
Viral Testing: Donors from the USA are tested for the standard FDA-required viral markers and found negative for HIV-1-NAT, HCV-NAT, HBV-NAT, WNV-NAT, anti-HIV ½, anti-HCV, HBsAg and syphilis using FDA-approved methods. Donors are also screened for Chagas and, when applicable, a licensed NAT for Babesia is performed.
Donors from Europe are tested for the standard European-required viral markers and found negative for HBsAg, anti-HBc, HIV-1/2-Ab, HCV-Ab, HIV-1-NAT, HCV-NAT, HBV-NAT, HAV-NAT, PVB19-NAT, HEV-NAT, WNV-NAT (tested from June to November) and syphilis.
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Grifols Bio Supplies offers high-quality products with various specifications from stock and customized specifications upon request.
|Anticoagulants||Blood Type||Storage Temperature||Other Options|
|ACD||Type A pos||Refrigerated (2-8 °C)||Dating Specific|
|Type A neg|
|Type B pos|
|K2 EDTA||Type B neg||Room Temperature (15-30 °C)|
|Type AB pos||Analytical Services|
|Type AB neg|
|Sodium Citrate||Type O pos||Frozen (<-20 °C)|
|Type O neg|
European source material customizations could vary. For more information on product availability or customization, please contact us here.
Additional analytical services
|SEROLOGICAL VIRAL TESTING||CONFIRMATORY TESTING||NUCLEIC ACID TESTING||OTHER|
|Syphilis (RPR)||Anti-HIV 1 Western Blot||HBV DNA Screening||Serum Protein Electrophoresis|
|Anti-Hbcore IgM||Anti-HIV-2 EIA||HCV RNA Screening||Total Protein|
|Anti-HBS||HBsAg Neutralization||HIV 1/2 RNA Screening||Sickle Cell Screening|
|Anti-T. cruzi (Chagas)||Syphilis (T. pallidum)-G||HAV RNA Screening||ALT|
|Cytomegalovirus Antibody Testing (IgG or IgM)||PARVO B19 DNA Screening|
|Toxoplasma Antibody Testing (IgG or IgM)||WNV RNA Screening|
|Epstein-Barr Virus Antibody Testing (IgG or IgM)||Zika RNA Screening|
Additional testing may be provided upon request
Testing only available for US source material
The information contained in these webpages are intended for a professional audience of pharmaceutical and in vitro diagnostic manufacturing personnel.